WC024i-FXS-Nluc1
This reporter cell line is a modified version of WC007i-FX13-2 engineered to knock in a Nano-luciferase gene into the endogenous human FMR1 gene. This reporter cell line detects FMR1 gene reactivation in human neural cells and can be a valuable resource to identify novel compounds for FMR1 gene reactivation studies.
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Cell Line Alias
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FX-iPSC-Nluc1 |
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Cell Type
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Modified Human iPS |
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Disease
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Fragile X syndrome |
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Genetic Alteration/Mutation
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FMR1 |
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Genetic Modification Keyword
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Reporter; Neural |
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Sex
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Male |
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Age at Collection
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8 Years |
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Genetically Related Cell Lines
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Reprogramming Method
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Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc) |
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Tissue Origin
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Skin |
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Provider
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University of Wisconsin - Dr. Anita Bhattacharyya and Dr. Xinyu Zhao |
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dbGaP Data
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hPSCReg ID
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NIH Approval
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Pub Med Abstract
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Related Products
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