UWWC1-2DS3
** This cell line contains an expected karyotypic abnormality consistent with the phenotype indicated in the "disease" field below. Please see the karyotype report in the Product Information & Testing PDF(s) linked below for more information.
This induced pluripotent stem (iPS) cell line, which serves as a model for Down Syndrome (Trisomy 21), was created by reprogramming a trisomy of 21 (Ts21) human fibroblast line.
Cell Line Alias
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2DS3 |
Cell Type
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Human iPS |
Disease
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Down syndrome, Trisomy 21 |
Genetic Alteration/Mutation
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47,XY,+21 (Trisomy 21) |
Sex
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Male |
Age at Collection
|
1 Months |
Genetically Related Cell Lines
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Reprogramming Method
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Non-integrating (Sendai: Oct4, Klf4, Sox2, cMyc) |
Provider
|
University of Wisconsin - Dr. Anita Bhattacharyya
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dbGaP Data
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hPSCReg ID
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NIH Approval
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Pub Med Abstract
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Related Products
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Collection(s)
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Down syndrome (Bhattacharyya) Collection
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